There is therefore a growing demand for appropriate nutrition interventions and targeted medical nutrition supplements or formulas to address patient needs, improve outcomes and help to reduce the costs of healthcare. Undernutrition and overnutrition can both seriously impact an individual’s risk for developing an NCD.
This has led patients to present with multiple co-morbidities creating more complex needs (e.g., need for multiple medications), putting significant pressure on healthcare and social systems. Life expectancy is increasing globally and the prevalence of age- and lifestyle-related non-communicable diseases (NCDs), such as cancer, heart disease, respiratory disease, type 2 diabetes, obesity, chronic kidney disease and dementia is rising. Well-designed intervention studies are required to optimize the effects of DHA and EPA in specific patient populations and to develop more personalized strategies for their use. However, it is important to note that data on the effects of omega-3 LCPUFAs are still inconsistent in many areas (e.g., cognitive decline) due to a range of factors that vary amongst the trials performed to date these factors include dose, timing and duration baseline omega-3 LCPUFA status and intake of other nutrients. Use of DHA and EPA in some conditions is already included in some relevant guidelines.
Evidence for benefits in cognitive health, age- and disease-related decline in muscle mass, cancer treatment, surgical patients and critical illness was identified. An expert group reviewed the data on omega-3 LCPUFAs in specific patient populations and medical conditions. The long-chain omega-3 polyunsaturated fatty acids (omega-3 LCPUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are known to reduce inflammation and promote its resolution, suggesting a beneficial role in various therapeutic areas. Inflammation plays a central role in NCDs, so targeting it is relevant to disease prevention and treatment. Effective nutrition interventions could be an important tool to address patient needs, improve clinical outcomes and reduce healthcare costs.
Consequently, older people and patients present with multi-morbidities and more complex needs, putting significant pressure on healthcare systems. Life expectancy is increasing and so is the prevalence of age-related non-communicable diseases (NCDs).
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